Bruce Kristal

Bruce Kristal, Ph.D.

Associate Professor of Medicine
617-525-3280
Harvard Catalyst Profile
Harvard Title

Associate Professor of Medicine

Administrative and Hospital Titles

Lead Investigator, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital

Address

221 Longwood Ave, LM322B, Boston, MA 02115

Publications View
N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.
Authors: Li W, Fotinos A, Wu Q, Chen Y, Zhu Y, Baranov S, Tu Y, Zhou EW, Sinha B, Kristal BS, Wang X.
Neurobiol Dis
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Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Authors: Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkilä V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, Mägi R, Dimitriou M, Garcia ME, Ho WK, Wright MJ, Rose LM, Magnusson PK, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJ, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs DR, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaëlsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, Männistö S, Perälä MM, Kähönen M, Lehtimäki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Döring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellström D, Hottenga JJ, Prokopenko I, Tönjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJ, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BH, Hu FB, Hyppönen E, Järvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, Chasman DI.
Mol Psychiatry
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Metabolomics in the developmental origins of obesity and its cardiometabolic consequences.
Authors: Hivert MF, Perng W, Watkins SM, Newgard CS, Kenny LC, Kristal BS, Patti ME, Isganaitis E, DeMeo DL, Oken E, Gillman MW.
J Dev Orig Health Dis
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Qualitative characterization of the rat liver mitochondrial lipidome using all ion fragmentation on an Exactive benchtop Orbitrap MS.
Authors: Bird SS, Stavrovskaya IG, Gathungu RM, Tousi F, Kristal BS.
Methods Mol Biol
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Soluble, prefibrillar a-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction.
Authors: Luth ES, Stavrovskaya IG, Bartels T, Kristal BS, Selkoe DJ.
J Biol Chem
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Identification of metabolites from liquid chromatography-coulometric array detection profiling: gas chromatography-mass spectrometry and refractionation provide essential information orthogonal to LC-MS/microNMR.
Authors: Gathungu RM, Bird SS, Sheldon DP, Kautz R, Vouros P, Matson WR, Kristal BS.
Anal Biochem
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N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.
Authors: Zhou H, Wang J, Jiang J, Stavrovskaya IG, Li M, Li W, Wu Q, Zhang X, Luo C, Zhou S, Sirianni AC, Sarkar S, Kristal BS, Friedlander RM, Wang X.
J Neurosci
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Dietary macronutrients modulate the fatty acyl composition of rat liver mitochondrial cardiolipins.
Authors: Stavrovskaya IG, Bird SS, Marur VR, Sniatynski MJ, Baranov SV, Greenberg HK, Porter CL, Kristal BS.
J Lipid Res
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Qualitative Characterization of the Rat Liver Mitochondrial Lipidome using LC-MS Profiling and High Energy Collisional Dissociation (HCD) All Ion Fragmentation.
Authors: Bird SS, Marur VR, Stavrovskaya IG, Kristal BS.
Metabolomics
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Method development for fecal lipidomics profiling.
Authors: Gregory KE, Bird SS, Gross VS, Marur VR, Lazarev AV, Walker WA, Kristal BS.
Anal Chem
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