Dr. Suzanne Bertisch discusses the most commonly used medications for sleep.
Below is a list of medications that are either approved by the FDA or are commonly used for the treatment of insomnia. Medications are most appropriate for short-term insomnia (i.e., several days or a few weeks) that has been triggered by an emotional or physical event. They should be used under the supervision of a clinician.
- Baldwin, David S., et al. "Benzodiazepines: risks and benefits. A reconsideration." Journal of psychopharmacology 27.11 (2013): 967-971.
- Center for Drug Evaluation and Research. “Boxed Warning for Risk of Serious Injuries Caused by Sleepwalking.” U.S. Food and Drug Administration, FDA.
- Ward, Curt R. "Ramelteon (Rozerem) for insomnia." American Family Physician 73.8 (2006): 1437.
- Emet, Mucahit, et al. "A review of melatonin, its receptors and drugs." The Eurasian journal of medicine 48.2 (2016): 135.
- Rosenberg, Russell, et al. "Comparison of Lemborexant with placebo and zolpidem tartrate extended release for the treatment of older adults with insomnia disorder: a phase 3 randomized clinical trial." JAMA network open 2.12 (2019): e1918254-e1918254.
- "Product Information. Belsomra (Suvorexant)." Merck Inc, Kenilworth, NJ.
- "Product Information. Dayvigo (Lemborexant)." Eisai Inc, Woodcliff Lake, NJ.
- Hajek, Goran, et al. "Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study." The Journal of clinical psychiatry 62.6 (2001): 453-463.
- Yi, Xiao-yan, et al. "Trazodone for the treatment of insomnia: a meta-analysis of randomized placebo-controlled trials." Sleep medicine 45 (2018): 25-32.
- Quetiapine. MedlinePlus. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a698019.html.
- Diphenhydramine. MedlinePlus. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682539.html.
- Doxylamine. MedlinePlus. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682537.html.
- Acetaminophen. MedlinePlus. U.S. National Library of Medicine. https://www.nlm.nih.gov/medlineplus/druginfo/meds/a681004.html.