On October 4, 2021, the Division of Sleep Medicine held its 20th Annual Sleep and Health Benefit virtually, given the COVID-19 pandemic and recommended social distancing guidelines within our Harvard Medical School community. Ying-Hui Fu, PhD, and Louis Ptáček, MD, Professors of Neurology at University of California, San Francisco, were both awarded the 2021 Harvard Medical School Division of Sleep Medicine Prize for their contributions to the field of Sleep Medicine. Charles A. Czeisler, MD, PhD, Baldino Professor of Sleep Medicine, Director of the Division of Sleep Medicine at Harvard Medical School and Chief of the Division of Sleep and Circadian Disorders in the Department of Medicine at Brigham and Women's Hospital in Boston, Massachusetts, presented opening remarks. Clifford Saper, MD, PhD, James Jackson Putnam Professor of Neurology and Neuroscience at Harvard Medical School and Chair and Head of the Department of Neurology at Beth Israel Deaconess Medical Center, presented the award.
View the 2021 Sleep and Health Benefit program here.
SCHEDULE
10:00 - 11:30 AM ET
HMS DSM Annual Faculty Meeting
10:00 - 11:30 AM ET
Introductory Meeting for HMS DSM Trainees with Prize Winners Ying-Hui Fu, Ph.D., and Louis Ptáček, M.D.
12:00 - 1:15 PM ET
Division of Sleep Medicine Annual Prize Lecture by Ying-Hui Fu, Ph.D., and Louis Ptáček, M.D.
“Insights from studying genetics and biology and human sleep behaviors”
Ying-Hui Fu, PhD
Professor of Neurology
Department of Neurology
Weill Institute for Neurosciences
University of California, San Francisco
Louis Ptáček, MD
John C. Coleman Distinguished Professor of Neurology
University of California, San Francisco
- Opening Remarks: Charles A. Czeisler, MD, PhD
Access the recording of the lecture by clicking here.
1:15 - 1:30 PM ET
Awarding of 2021 Harvard Medical School Division of Sleep Medicine Prize to Ying-Hui Fu, Ph.D., and Louis Ptáček, M.D.
- Award Presentation: Clifford B. Saper, MD, PhD
1:30 - 2:30 PM ET
Executive Council Meeting
2:30 - 4:30 PM ET
Data Blitz
- Data Blitz Website (Password: SLEEP2021)
4:30 - 5:30 PM ET
Reception
- Opening Remarks: Charles A. Czeisler, MD, PhD
- Data Blitz Awards Presented by: Thomas E. Scammell, MD
5:30 - 6:30 PM ET
Evening Public Lecture by Ying-Hui Fu, Ph.D., and Louis Ptáček, M.D.
“Serendipity, Ambition, and Delight: Insights from study of human sleep genetics.”
- Opening Remarks: Charles A. Czeisler, MD, PhD
- Moderator: Jeanne F. Duffy, MBA, MS, PhD
Register now ! Have questions related to the lecture? Submit your questions here!
Access the recording of the public lecture by clicking here.
Support for the 2021 Sleep and Health Benefit was generously provided by the following individuals and organizations:
Underwriter Benefactors Patron Sponsors|
Apnimed |
f.lux |
|
Timeshifter |
Project Sleep |
Support in 2021 for the Harvard Medical School Division of Sleep Medicine Sleep Matters Initiative was generously provided by the following organizations:
- Bryte Labs, FortyW Inc.
- SleepCycle AB
- Takeda Pharmaceutical Company
Support in 2021-2022 for the Harvard Medical School Division of Sleep Medicine Sleep Grand Rounds Program was generously provided by the following organizations:
- Harmony Biosciences
- Jazz Pharmaceuticals
- NeuroCare, Inc.
- Philips Respironics
- Regional Home Care
For 25 years, support for the Harvard Medical School Training Program in Sleep, Circadian and Respiratory Neurobiology administered by the Brigham and Women’s Hospital has been provided by a training grant from the National Heart, Lung and Blood Institute.
Data Blitz
Clinical Sleep Disorders
| Winner | Honorable Mention |
| Michael Vazquez | Gonzalo Labarca, M.D. |
- Margaret Blattner, M.D., Ph.D. - REM sleep distribution in patients with prolonged sleep duration
- Joon Chung, Ph.D. - Multidimensional sleep health - concepts and approaches
- Danielle Clarkson-Townsend, M.P.H., Ph.D. - Associations between shift work, sleep, and adverse pregnancy outcomes in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b)
- Larissa Engert, Ph.D. - The effect of glucocorticoids on inflammatory marker expression in human monocytes during sleep restriction and recovery
- Wolfgang Ganglberger, MSc. - Sleep in the Intensive Care Unit: Staging Sleep with Heart Rate Variability, Breathing, and Artificial Intelligence
- Michael Goldstein, Ph.D. - Interactive effects of slow-paced breathing and mindfulness on sleep and overnight heart rate variability: A three-arm pilot RCT
- Seyni Gueye-Ndiaye, M.D. - Environmental factors affecting pediatric sleep
- Gonzalo Labarca, M.D. - Association between Obstructive Sleep Apnea delta heart rate with incident Atrial fibrillation in a community-based cohort
- Kiran Maski, M.D., M.P.H. - Development and Validation of Pediatric Hypersomnia Screening Survey
- Edward Pace-Schott, Ph.D. - Generalized Anxiety Disorder with and without Insomnia Disorder: Sleep quality, anxiety and neural activations accompanying fear conditioning and extinction
- Alicia Stokes, Ph.D. - Thought Control Strategies and Insomnia Severity in Young Adult African Americans
- Michael Vazquez - Sleep Hygiene as an Intervention to Lower Blood Pressure
- Heming Wang, Ph.D. - Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based mendelian randomization study
Circadian, Memory and other aspects of Sleep Physiology
| Winner | Honorable Mentions |
| Maia Feik Reinhart | Chenlu Gao, Ph.D. & Raphael Knaier, Ph.D. |
- Enmanuelle Pardilla-Delgado, Ph.D. - Laboratory-controlled circadian disruption decreases ability of actigraphy to accurately measure sleep
- Sara Abbaspour, Ph.D. - The effect of time of day of COVID-19 vaccination on side effects”.
- Bryan Baxter, Ph.D. - Measuring the temporal coupling of slow oscillations, spindles, and hippocampal ripples in relation to procedural memory in humans
- Ryan Bottary, M.A.- Age and Chronotype Associated with Sleep Timing Changes During COVID-19-Related Lockdowns in the US
- Maia Feik Reinhart - Associations of sleep-wake and circadian timing with dietary fat, cholesterol, and caloric intake.”
- Chenlu Gao, Ph.D. - Validation of the ezActi application for scoring daytime and nighttime sleep using actigraphy & Sleep disturbance and incident Alzheimer's Disease: a UK Biobank study of 502,402 middle-aged to older participants
- Kevin Jiang - Light exposure and its association with neurobehavioral capabilities and self-reported well-being
- Raphael Knaier, Ph.D. - Diurnal variation in physical performance: a meta-analysis
- Celina Pluim, M.A. - Sleep and Cognition in Older Adults: Examining the Role of Circadian Rhythms
- Jingyi Qian, Ph.D. - Longitudinal Changes in Glycemic Control by Timing of Physical Activity in The Look AHEAD Study
- Rachel Soemedi, Ph.D. - Sex-biased genetic landscape associated with sleep disorders
- Aaron Strong - Urinomics markers for predictions of neurobehavioral performance in response to sleep loss
- Hui-Wen Yang, Ph.D. - Polygenetic risk score and integrated biomarker of motor activity for the risk of AD
Basic Science
| Winner | Honorable Mention |
| Sydney Aten, Ph.D. | Ilaria Barone, Ph.D. |
- Sydney Aten, Ph.D. - SynGAP is expressed in the murine suprachiasmatic nucleus and regulates circadian-gated locomotor activity and light-entrainment capacity
- Ilaria Barone, Ph.D. - Phosphorylation regulates synaptic BMAL1 and synaptic vesicles dynamics
- Jessica Brooks, B.A. - CLOCK as a prion-like stress sensor
- Roberto De Luca, Ph.D. - Noradrenaline and acetylcholine inhibit sleep-promoting neurons of ventrolateral preoptic area through a local GABAergic circuit
- Bridget Fitzgerald, B.A. - Norepinephrine Tone Across Sleep/Wake States in Medial Prefrontal Cortex
- Michael Gulledge, B.A. - Determining the Behavioral and Neurobiological Effects of Oxycodone Withdrawal on Sleep in Rats
- Adam Joyal - The Role of Oxytocin in the Lateral Hypothalamus
- Peter Kalugin - Dynamic tracking of cerebrospinal fluid composition in vivo
- Jonathan Lipton, M.D., Ph.D. - Synaptic BMAL1 Phosphorylation Regulates Diurnal Vesicle Dynamics
- Torrey Mandigo, Ph.D. - A conserved role for the N-glycosylation pathway in sleep and seizures