Many faculty in the HMS Division of Sleep Medicine conduct research in human subjects. If you are interested in participating in a research study, please call or send an email to the contact person indicated for that study.

For a complete list of sleep research studies at HMS-affiliated hospitals, please visit Rally.

  • Do you have untreated sleep apnea?

    Brigham and Women’s Hospital seeks male and female volunteers aged 21 to 70, with obstructive sleep apnea or suspected sleep apnea who are not being treated, to participate in a research study investigating how medication may improve sleep apnea in some patients.  

    The study involves one screening visit (about one hour) and four overnights (about 12 hours each) in our Sleep Research Lab at Brigham and Women’s Hospital.  

    You will receive up to $900 total for participating in this study.

    For more information please call Nicole at (617) 732-8977 or e-mail ncalianese@bwh.harvard.edu.

    Location: Brigham and Women's Hospital
    Study title: A Novel Pharmacological Therapy for Obstructive Sleep Apnea
    Faculty member submitting this notice: Scott Sands, PhD
    Contact for this notice: Lauren Hess, lhess1@bwh.harvard.edu, 617-732-8976
    IRB expiration: 3/17/2021

  • Do you wait to sleep until the afternoon after your night shift? Take part in a survey study!

    Shiftwork and Sleep Habits Survey!

    If you:
    o    Are 18 years old or older
    o    Currently working several night shifts in a row

    You may be eligible to participate in a daily online 5-minute survey to contribute to our understanding of shiftwork, sleep, and daily routines. You will receive a $25 gift card after completing 2 weeks of the daily survey. Use the link below to get started.

    https://is.gd/sleephabits

     

    Protocol # 2018-P-000124
    IRB that approved this notice: MGB IRB
    IRB approval expiration date: 1/25/2022
    Study title: Evaluation of work, leisure, and sleep habits in shift workers
    Faculty member responsible for this notice: Jeanne Duffy, PhD, MBA
    Contact for this notice: Audra Murphy, nightwork@research.bwh.harvard.edu, 617-525-8904

     

  • Help Us Learn More About Circadian Rhythms! 5-day Research Study

    The Division of Sleep Medicine at Brigham & Women’s Hospital is seeking healthy volunteers ages 21-35 to participate in a sleep research study. You must be a non-smoker and not on any medications. You will complete 4 screening visits and must keep a regular sleep schedule for 2 to 4 weeks. If eligible, you will live 5 consecutive days and nights at the sleep research laboratory within the hospital. The purpose of this study is to see if the body’s internal ‘clock’ time can be estimated from a single blood sample. Receive up to $1,800 For more information, call 617-525-8813, e-mail us at BodyClockStudy@research.bwh.harvard.edu or visit https://rally.partners.org/study/bodyclockstudy

    Protocol # 2019-P-001247
    IRB approval expiration date:
    3/22/2022
    IRB that approved this notice: MGB IRB
    Location of the study: Brigham and Women's Hospital
    Study title: Biomarkers for Circadian Timing
    Faculty member responsible for this notice:
    Jeanne Duffy, PhD, MBA
    Contact for this notice:
    Mia Friedman, bodyclockstudy@research.bwh.harvard.edu, 617-525-8813

     

     

     

  • Interaction of Melatonin and MTNR1B Genotype on Glucose Control

    Brigham and Women’s Hospital researchers need you!  Looking for adults between the ages of 21 - 55.
    This study will be performed in healthy individuals with genetic variation in a gene called MTNR1B. This gene influences the regulation of blood sugar and has been associated with type 2 diabetes risk. Your genes are passed down from your parents and then passed on to your children. If you are eligible and interested in enrolling in our research study we collect a saliva or blood sample to test your genetic material for the MTNR1B genetic variation.

    Requirements:
    Prospective subjects must be healthy Caucasian non-smokers between the ages of 21-55, live in New England, and off most medications (birth control is acceptable).

    Study Description:
    •    Medical Screening at no cost to you.
    •    3 - 4 short screening visits
    •    Must live in New England
    •    One 5-day in-laboratory stay, and/or three 2-day in-laboratory stays at Brigham and Women’s Hospital
    •    Willing to take melatonin
    •    Payment approximately $1,700 for your time.” to “Payment Total for research visits: $1700 for 5-day stay, $2100 for three 2-day stays, $3,800 for both protocols

    To see if you are eligible, please fill out our online survey at
    https://clinicaltrials.partners.org/study/melatonin and indicate interest as “Melatonin Study”.

    Location of the study: Brigham and Women’s Hospital
    Study title: Interaction of Melatonin and MTNR1B Genotype on Glucose Control
    Faculty member responsible for this notice: Frank Scheer, PhD
    Contact for this notice: Hoa Nguyen, hnguyen48@bwh.harvard.edu
    IRB expiration: 3/14/2021

  • Are you a healthcare worker who works night shifts? Take part in a research study about sleep and performance!

    Shiftwork Research Study! 

    We are seeking health care workers who: 

    • Are 50-65 years old 

    • Work regular 8-hour overnight shifts 

    You may be eligible to participate in a 2-week research study to help us understand how the timing and duration of sleep impacts performance, well-being, and mood. You will wear a wrist activity monitor, complete daily questionnaires, and sleep at specific times. No visits to our research lab will be required, all study procedures will be carried out remotely. Payment is up to $500.

    Click on the survey link below to get started:

    https://is.gd/shiftworkersurvey  

    Protocol # 2018-P-002341
    IRB that approved this notice: MGB IRB
    IRB approval expiration date: 10/29/2022
    Location of the study: Brigham and Women’s Hospital
    Study title: Sleep and Circadian Treatments for Shift Workers
    Faculty member responsible for this notice: Jeanne Duffy, PhD, MBA
    Contact for this notice: Audra Murphy, nightwork@research.bwh.harvard.edu, 617-525-8904

  • 10-day inpatient study of sleep deprivation

    Research study looking at effects of sleep on health and neurobehavioral performance needs volunteers!

    We want to learn more about how different sleep patterns affect health and other outcomes. If you participate in this study, you will have up to 4 weeks of screening and be asked to live in our laboratory for 10 days.

    We are conducting this study because we are interested in discovering biomarkers associated with neurobehavioral or cognitive impairment during sleep loss and mistimed sleep.

    https://rally.partners.org/study/faa_sleep

    sleepfaa@partners.org / 617-732-4311

    Protocol # 2019P002480
    IRB that approved this notice: MGB IRB
    IRB approval expiration date: 11/03/2022
    Location of the study: Brigham and Women’s Hospital
    Study title: Comparison across multiple types of sleep deprivation
    Faculty member responsible for this notice: Elizabeth B Klerman, MD, PhD
    Contact for this notice: Dr. Elizabeth B Klerman, 617-732-8145

  • Help Us Learn More About Sleep!

    If you are:

    · 20-40 years old 

    · Non smoker 

    · Healthy and taking no medication 

    You may be eligible for a 33-day sleep research study at Brigham & Women’s Hospital. There will be a 2 week screening period. Must be willing to spend 33 consecutive days and nights in our facility. Receive up to $6,250

     

    Call 617-525-8838 or email BWHALANstudy@partners.org

    Protocol # 2021P000961
    IRB that approved this notice: MGB IRB
    IRB approval expiration date: 06/21/2022
    Location of the study: Brigham and Women’s Hospital
    Study title: Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction
    Faculty member responsible for this notice: Mia Friedman​​​​​​​
    Contact for this notice: Mia Friedman, BWHALANstudy@partners.org, 617-525-8813