Bruce Kristal

Bruce Kristal, Ph.D.

Associate Professor of Medicine
617-525-3280
Harvard Catalyst Profile
Harvard Title

Associate Professor of Medicine

Administrative and Hospital Titles

Lead Investigator, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital

Address

221 Longwood Ave, LM322B, Boston, MA 02115

Publications View
Metabolomics: opening another window into aging.
Authors: Kristal BS, Shurubor YI.
Sci Aging Knowledge Environ
View full abstract on Pubmed
pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification.
Authors: Klyachko NL, Shchedrina VA, Efimov AV, Kazakov SV, Gazaryan IG, Kristal BS, Brown AM.
J Biol Chem
View full abstract on Pubmed
The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?
Authors: Stavrovskaya IG, Kristal BS.
Free Radic Biol Med
View full abstract on Pubmed
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Authors: Tang TS, Slow E, Lupu V, Stavrovskaya IG, Sugimori M, Llinás R, Kristal BS, Hayden MR, Bezprozvanny I.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Metabolomic analysis and signatures in motor neuron disease.
Authors: Rozen S, Cudkowicz ME, Bogdanov M, Matson WR, Kristal BS, Beecher C, Harrison S, Vouros P, Flarakos J, Vigneau-Callahan K, Matson TD, Newhall KM, Beal MF, Brown RH, Kaddurah-Daouk R.
Metabolomics
View full abstract on Pubmed
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
Authors: Ferrante RJ, Ryu H, Kubilus JK, D'Mello S, Sugars KL, Lee J, Lu P, Smith K, Browne S, Beal MF, Kristal BS, Stavrovskaya IG, Hewett S, Rubinsztein DC, Langley B, Ratan RR.
J Neurosci
View full abstract on Pubmed
Nutrition and physical activity and chronic disease prevention: research strategies and recommendations.
Authors: Prentice RL, Willett WC, Greenwald P, Alberts D, Bernstein L, Boyd NF, Byers T, Clinton SK, Fraser G, Freedman L, Hunter D, Kipnis V, Kolonel LN, Kristal BS, Kristal A, Lampe JW, McTiernan A, Milner J, Patterson RE, Potter JD, Riboli E, Schatzkin A, Yates A, Yetley E.
J Natl Cancer Inst
View full abstract on Pubmed
The mitochondrial permeability transition as a target for neuroprotection.
Authors: Kristal BS, Stavrovskaya IG, Narayanan MV, Krasnikov BF, Brown AM, Beal MF, Friedlander RM.
J Bioenerg Biomembr
View full abstract on Pubmed
Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.
Authors: Stavrovskaya IG, Narayanan MV, Zhang W, Krasnikov BF, Heemskerk J, Young SS, Blass JP, Brown AM, Beal MF, Friedlander RM, Kristal BS.
J Exp Med
View full abstract on Pubmed
Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice.
Authors: Zhu S, Li M, Figueroa BE, Liu A, Stavrovskaya IG, Pasinelli P, Beal MF, Brown RH, Kristal BS, Ferrante RJ, Friedlander RM.
J Neurosci
View full abstract on Pubmed