Harvard Title
Associate Professor of Medicine
Administrative and Hospital Titles
Lead Investigator, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital
Address
221 Longwood Ave, LM322B, Boston, MA 02115
Publications View
Purine catabolism: links to mitochondrial respiration and antioxidant defenses?
Authors: Kristal BS, Vigneau-Callahan KE, Moskowitz AJ, Matson WR.
Arch Biochem Biophys
View full abstract on Pubmed
Arch Biochem Biophys
View full abstract on Pubmed
Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition.
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia.
Authors: Park LC, Zhang H, Sheu KF, Calingasan NY, Kristal BS, Lindsay JG, Gibson GE.
J Neurochem
View full abstract on Pubmed
J Neurochem
View full abstract on Pubmed
A DLST genotype associated with reduced risk for Alzheimer's disease.
Authors: Sheu KF, Brown AM, Kristal BS, Kalaria RN, Lilius L, Lannfelt L, Blass JP.
Neurology
View full abstract on Pubmed
Neurology
View full abstract on Pubmed
Ganglioside GD3, the mitochondrial permeability transition, and apoptosis.
The mitochondrial permeability transition: the brain's point of view.
Authors: Dubinsky JM, Brustovetsky N, Pinelis V, Kristal BS, Herman C, Li X.
Biochem Soc Symp
View full abstract on Pubmed
Biochem Soc Symp
View full abstract on Pubmed
Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population.
Authors: Sheu KF, Brown AM, Haroutunian V, Kristal BS, Thaler H, Lesser M, Kalaria RN, Relkin NR, Mohs RC, Lilius L, Lannfelt L, Blass JP.
Ann Neurol
View full abstract on Pubmed
Ann Neurol
View full abstract on Pubmed
Simultaneous analysis of the majority of low-molecular-weight, redox-active compounds from mitochondria.
Dietary restriction augments protection against induction of the mitochondrial permeability transition.
Norepinephrine transmitter metabolite generates free radicals and activates mitochondrial permeability transition: a mechanism for DOPEGAL-induced apoptosis.