Harvard Title
Warren M. Zapol Professor of Anaesthesia
Administrative Title(s)
Director, Neuroscience Statistics Research Laboratory, Department of Anesthesia and Critical Care, Massachusetts General Hospital
Anesthetist, Department of Anesthesia, Massachusetts General Hospital
Co-Director, Harvard-MIT Division of Health Sciences and Technology
Other Affiliation(s)
Professor of Computational Neuroscience
Professor of Health Sciences and Technology, Massachusetts Institute of Technology
Address
Dept. of Anesthesia and Critical Care, Massachusetts General Hospital
55 Fruit Street, Gray-Bigelow 444
Boston, MA 02114
Publications View
Modulatory dynamics mark the transition between anesthetic states of unconsciousness.
Authors: Adam E, Kwon O, Montejo KA, Brown EN.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Sustaining wakefulness: Brainstem connectivity in human consciousness.
Authors: Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC.
bioRxiv
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bioRxiv
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Recovery From Acute Respiratory Distress Syndrome Is Associated With Increasing Alpha Power in the Frontal Electroencephalogram During Propofol Sedation: A Case Report.
Rapid thalamocortical network switching mediated by cortical synchronization underlies propofol-induced EEG signatures: a biophysical model.
Authors: Soplata AE, Adam E, Brown EN, Purdon PL, McCarthy MM, Kopell N.
J Neurophysiol
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J Neurophysiol
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Propofol Mediated Unconsciousness Disrupts Progression of Sensory Signals through the Cortical Hierarchy.
Authors: Tauber JM, Brincat SL, Stephen EP, Donaghue JA, Kozachkov L, Brown EN, Miller EK.
bioRxiv
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bioRxiv
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Breathe-squeeze: pharmacodynamics of a stimulus-free behavioural paradigm to track conscious states during sedation?.
Authors: Guay CS, Hight D, Gupta G, Kafashan M, Luong AH, Avidan MS, Brown EN, Palanca BJA.
Br J Anaesth
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Br J Anaesth
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Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology.
Authors: Tian F, Lewis LD, Zhou DW, Balanza GA, Paulk AC, Zelmann R, Peled N, Soper D, Santa Cruz Mercado LA, Peterfreund RA, Aglio LS, Eskandar EN, Cosgrove GR, Williams ZM, Richardson RM, Brown EN, Akeju O, Cash SS, Purdon PL.
Nat Commun
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Nat Commun
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Propofol disrupts alpha dynamics in functionally distinct thalamocortical networks during loss of consciousness.
Authors: Weiner VS, Zhou DW, Kahali P, Stephen EP, Peterfreund RA, Aglio LS, Szabo MD, Eskandar EN, Salazar-Gomez AF, Sampson AL, Cash SS, Brown EN, Purdon PL.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial.
Authors: Qu JZ, Mueller A, McKay TB, Westover MB, Shelton KT, Shaefi S, D'Alessandro DA, Berra L, Brown EN, Houle TT, Akeju O.
EClinicalMedicine
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EClinicalMedicine
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Desynchronizing the sleep---wake cycle from circadian timing to assess their separate contributions to physiology and behaviour and to estimate intrinsic circadian period.
Authors: Wang W, Yuan RK, Mitchell JF, Zitting KM, St Hilaire MA, Wyatt JK, Scheer FAJL, Wright KP, Brown EN, Ronda JM, Klerman EB, Duffy JF, Dijk DJ, Czeisler CA.
Nat Protoc
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Nat Protoc
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