In memoriam: J. Woodland (Woody) Hastings

In memoriam: J. Woodland (Woody) Hastings, Ph.D.

Paul C. Mangelsdorf Professor of Natural Sciences

Professor of Molecular and Cellular Biology

Faculty Information
Publications

Harvard Titles

Paul C. Mangelsdorf Professor of Natural Sciences, Harvard University Faculty of Arts and Sciences
Professor, Department of Molecular and Cellular Biology, Harvard University Faculty of Arts and Sciences

Biography

Obituary

Selected Publications

Silva JR, Amaral DT, Hastings JW, Wilson T, Viviani VR. A transcriptional and
proteomic survey of Arachnocampa luminosa (Diptera: Keroplatidae) lanterns gives
insights into the origin of bioluminescence from the Malpighian tubules in
Diptera. Luminescence. 2015 Nov;30(7):996-1003. doi: 10.1002/bio.2850. Epub 2015 Feb 10. PMID: 25676901.

Hastings JW. Circadian Rhythms in Dinoflagellates: What Is the Purpose of
Synthesis and Destruction of Proteins? Microorganisms. 2013 Sep 18;1(1):26-32.
doi: 10.3390/microorganisms1010026. PMID: 27694762; PMCID: PMC5029499.

Hastings JW. The Gonyaulax clock at 50: translational control of circadian
expression. Cold Spring Harb Symp Quant Biol. 2007;72:141-4. doi:
10.1101/sqb.2007.72.026. PMID: 18419271.

Liu L, Hastings JW. Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species.
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):696-701. Epub 2006 Nov 27. [PMID: 17130452]

Nealson KH, Hastings JW. Quorum sensing on a global scale: massive numbers of bioluminescent bacteria make milky seas.
Appl Environ Microbiol. 2006 Apr;72(4):2295-7. [PMID: 16597922]

Schultz LW, Liu L, Cegielski M, Hastings JW. Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole.
Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1378-83. Epub 2005 Jan 21. [PMID: 15665092]

Liu L, Wilson T, Hastings JW. Molecular evolution of dinoflagellate luciferases, enzymes with three catalytic domains in a single polypeptide.
Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16555-60. Epub 2004 Nov 15. [PMID:15545598]

Hastings JW. Bacterial quorum-sensing signals are inactivated by mammalian cells.
Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):3993-4. Epub 2004 Mar 15. [PMID: 15024108]

Okamoto OK, Hastings JW. Genome-wide analysis of redox-regulated genes in a dinoflagellate.
Gene. 2003 Dec 4;321:73-81. [PMID: 14636994]

Rossini C, Taylor W, Fagan T, Hastings JW. Lifetimes of mRNAs for clock-regulated proteins in a dinoflagellate.
Chronobiol Int. 2003 Nov;20(6):963-76. [PMID: 14680137]

Okamoto OK, Hastings JW. Novel dinoflagellate clock-related genes identified through microarray analysis.
Journal of Phycology. 2003; 39(3): 519-526.

Comolli JC, Fagan T, Hastings JW. A type-1 phosphoprotein phosphatase from a dinoflagellate as a possible component of the circadian mechanism.
J Biol Rhythms. 2003 Oct;18(5):367-76. [PMID: 14582853]

Hastings JW. Fifty years of fun.
J Biol Rhythms. 2001 Feb;16(1):5-18. [PMID: 11220778]

Comolli JC, Hastings JW. Novel effects on the Gonyaulax circadian system produced by the protein kinase inhibitor staurosporine.
J Biol Rhythms. 1999 Feb;14(1):11-9. [PMID: 10036988]

Knaust R, Urbig T, Li LM, Taylor W, Hastings JW. The circadian rhythm of bioluminescence in Pyrocystis is not due to differences in the amount of luciferase: A comparative study of three bioluminescent marine dinoflagellates.
Journal of Phycology. 1998; 34(1): 167-172.

Mittag M, Eckerskorn C, Strupat K, Hastings JW. Differential translational initiation of lbp mRNA is caused by a 5' upstream open reading frame.
FEBS Lett. 1997 Jul 14;411(2-3):245-50. [PMID: 9271214]

Techel D, Chuang E, Lee DH, Comolli J, Hastings JW. Changes in the ultrastructural localization of mRNA for a circadian regulated protein.
Mol Mar Biol Biotechnol. 1996 Dec;5(4):241-8. [PMID: 8983193]

Comolli J, Taylor W, Rehman J, Hastings JW. Inhibitors of serine/threonine phosphoprotein phosphatases alter circadian properties in Gonyaulax polyedra.
Plant Physiol. 1996 May;111(1):285-91. [PMID: 8685268]

Mittag M; Hastings JW. Exploring the signaling pathway of circadian bioluminescence.
Physiologia Plantarum. 1996; 96(4): 727-732.

Books, Reviews, Chapters, etc.

Hastings JW. The Gonyaulax clock at 50: translational control of circadian expression.
Cold Spring Harb Symp Quant Biol. 2007;72:141-4. Review. [PMID:18419271]

Hastings JW, Morin JG. Photons for reporting molecular events: green fluorescent protein and four luciferase systems.
Methods Biochem Anal. 2006;47:15-38. Review. [PMID: 16335708]

Hastings JW. Fifty years of fun.
J Biol Rhythms. 2001 Feb;16(1):5-18. [PMID: 11220778]