Harvard Title
Professor of Anaesthesia
Administrative and Hospital Titles
Associate Geneticist, Center for Genomic Medicine Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital
Director of Genetics of Sleep and Circadian Research Program in Sleep Epidemiology, Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital
Associate Member, Broad Institute
Address
Massachusetts General Hospital
Simches Research Ctr
185 Cambridge Street, CPZN 5.802
Boston, MA 02114
Publications View
Greater Cognitive Deficits with Sleep-disordered Breathing among Individuals with Genetic Susceptibility to Alzheimer Disease. The Multi-Ethnic Study of Atherosclerosis.
Authors: Johnson DA, Lane J, Wang R, Reid M, Djonlagic I, Fitzpatrick AL, Rapp SR, Charles LE, O'Hara R, Saxena R, Redline S.
Ann Am Thorac Soc
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Ann Am Thorac Soc
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A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Authors: Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M, Gabriel S, Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC.
Diabetes
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Diabetes
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Sleep and cognitive performance: cross-sectional associations in the UK Biobank.
Authors: Kyle SD, Sexton CE, Feige B, Luik AI, Lane J, Saxena R, Anderson SG, Bechtold DA, Dixon W, Little MA, Ray D, Riemann D, Espie CA, Rutter MK, Spiegelhalder K.
Sleep Med
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Sleep Med
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Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis.
Authors: Yousri NA, Bayoumy K, Elhaq WG, Mohney RP, Emadi SA, Hammoudeh M, Halabi H, Masri B, Badsha H, Uthman I, Plenge R, Saxena R, Suhre K, Arayssi T.
Sci Rep
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Sci Rep
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A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.
Authors: Saxena R, Plenge RM, Bjonnes AC, Dashti HS, Okada Y, Gad El Haq W, Hammoudeh M, Al Emadi S, Masri BK, Halabi H, Badsha H, Uthman IW, Margolin L, Gupta N, Mahfoud ZR, Kapiri M, Dargham SR, Aranki G, Kazkaz LA, Arayssi T.
Arthritis Rheumatol
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Arthritis Rheumatol
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Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia.
Authors: Spracklen CN, Smith CJ, Saftlas AF, Triche EW, Bjonnes A, Keating BJ, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK.
Hypertens Pregnancy
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Hypertens Pregnancy
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Circadian Rhythms in Plasma Brain-derived Neurotrophic Factor Differ in Men and Women.
Authors: Cain SW, Chang AM, Vlasac I, Tare A, Anderson C, Czeisler CA, Saxena R.
J Biol Rhythms
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J Biol Rhythms
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Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.
Authors: Lane JM, Liang J, Vlasac I, Anderson SG, Bechtold DA, Bowden J, Emsley R, Gill S, Little MA, Luik AI, Loudon A, Scheer FA, Purcell SM, Kyle SD, Lawlor DA, Zhu X, Redline S, Ray DW, Rutter MK, Saxena R.
Nat Genet
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Nat Genet
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Phenotype and Tissue Expression as a Function of Genetic Risk in Polycystic Ovary Syndrome.
Relationship between polycystic ovary syndrome and ancestry in European Americans.