Harvard Title
Associate Professor of Psychiatry
Other Affiliations
Department of Psychiatry, Brigham and Women's Hospital
Senior Associate, Broad Institute, Stanley Center for Psychiatric Research
Address
Brigham and Women's Hospital
Dept. of Psychiatry, Rm 394
221 Longwood Ave
Boston MA 02115
Publications View
The genome-wide patterns of variation expose significant substructure in a founder population.
Authors: Jakkula E, Rehnström K, Varilo T, Pietiläinen OP, Paunio T, Pedersen NL, deFaire U, Järvelin MR, Saharinen J, Freimer N, Ripatti S, Purcell S, Collins A, Daly MJ, Palotie A, Peltonen L.
Am J Hum Genet
View full abstract on Pubmed
Am J Hum Genet
View full abstract on Pubmed
Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study.
Authors: Perlis RH, Moorjani P, Fagerness J, Purcell S, Trivedi MH, Fava M, Rush AJ, Smoller JW.
Neuropsychopharmacology
View full abstract on Pubmed
Neuropsychopharmacology
View full abstract on Pubmed
The positives, protocols, and perils of genome-wide association.
Association of reading disability on chromosome 6p22 in the Afrikaner population.
Authors: Platko JV, Wood FB, Pelser I, Meyer M, Gericke GS, O'Rourke J, Birns J, Purcell S, Pauls DL.
View full abstract on Pubmed
View full abstract on Pubmed
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.
Authors: Korn JM, Kuruvilla FG, McCarroll SA, Wysoker A, Nemesh J, Cawley S, Hubbell E, Veitch J, Collins PJ, Darvishi K, Lee C, Nizzari MM, Gabriel SB, Purcell S, Daly MJ, Altshuler D.
Nat Genet
View full abstract on Pubmed
Nat Genet
View full abstract on Pubmed
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
Authors: Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N.
Nat Genet
View full abstract on Pubmed
Nat Genet
View full abstract on Pubmed
50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.
Authors: Broom WJ, Greenway M, Sadri-Vakili G, Russ C, Auwarter KE, Glajch KE, Dupre N, Swingler RJ, Purcell S, Hayward C, Sapp PC, McKenna-Yasek D, Valdmanis PN, Bouchard JP, Meininger V, Hosler BA, Glass JD, Polack M, Rouleau GA, Cha JH, Hardiman O, Brown RH.
Amyotroph Lateral Scler
View full abstract on Pubmed
Amyotroph Lateral Scler
View full abstract on Pubmed
Whole-genome association study of bipolar disorder.
Authors: Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM.
Mol Psychiatry
View full abstract on Pubmed
Mol Psychiatry
View full abstract on Pubmed
Further evidence of association between two NET single-nucleotide polymorphisms with ADHD.
Authors: Kim JW, Biederman J, McGrath CL, Doyle AE, Mick E, Fagerness J, Purcell S, Smoller JW, Sklar P, Faraone SV.
Mol Psychiatry
View full abstract on Pubmed
Mol Psychiatry
View full abstract on Pubmed
Influence of RGS2 on anxiety-related temperament, personality, and brain function.
Authors: Smoller JW, Paulus MP, Fagerness JA, Purcell S, Yamaki LH, Hirshfeld-Becker D, Biederman J, Rosenbaum JF, Gelernter J, Stein MB.
Arch Gen Psychiatry
View full abstract on Pubmed
Arch Gen Psychiatry
View full abstract on Pubmed