
Zhigang He, B.M., Ph.D.
Professor of Neurology, Boston Children's Hospital
Professor of Ophthalmology, Boston Children's Hospital
Harvard Titles
Professor of Neurology and Opthalmology
Other Affiliations
Departments of Neurology and Opthalmology, Boston Children's Hospital
Address
Children's Hospital
6 Duxbury Rd
3 Blackfan Circle
Boston MA 02115
Publications View
EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans.
Authors: Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, Kim JA, Lin E, Tessier-Lavigne M, Chen DF, He Z.
Science
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Science
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A local mechanism mediates NAD-dependent protection of axon degeneration.
Authors: Wang J, Zhai Q, Chen Y, Lin E, Gu W, McBurney MW, He Z.
J Cell Biol
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J Cell Biol
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A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.
Authors: Park JB, Yiu G, Kaneko S, Wang J, Chang J, He XL, Garcia KC, He Z.
Neuron
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Neuron
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PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration.
Authors: Sivasankaran R, Pei J, Wang KC, Zhang YP, Shields CB, Xu XM, He Z.
Nat Neurosci
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Nat Neurosci
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Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.
The Nogo signaling pathway for regeneration block.
Signaling mechanisms of the myelin inhibitors of axon regeneration.
Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration.
Authors: Zhai Q, Wang J, Kim A, Liu Q, Watts R, Hoopfer E, Mitchison T, Luo L, He Z.
Neuron
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Neuron
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P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp.
Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth.
Authors: Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, He Z.
Nature
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Nature
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