Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

From Science Direct

In their recent study published in Cell Metabolism, Drs. Vujović, Qian, Garaulet, Scheer, and colleagues found that late eating increased hunger, modified appetite-regulating hormones, decreased daytime energy expenditure, and altered adipose tissue gene expression.


  • Late eating increases waketime hunger and decreases 24-h serum leptin
  • Late eating decreases waketime energy expenditure and 24-h core body temperature
  •  Late eating alters adipose tissue gene expression favoring increased lipid storage
  • Combined, these changes upon late eating may increase obesity risk in humans

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