Harvard Title
Professor of Anaesthesia
Administrative and Hospital Titles
Associate Geneticist, Center for Genomic Medicine Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital
Director of Genetics of Sleep and Circadian Research Program in Sleep Epidemiology, Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital
Associate Member, Broad Institute
Address
Massachusetts General Hospital
Simches Research Ctr
185 Cambridge Street, CPZN 5.802
Boston, MA 02114
Publications View
Genome-wide association analysis of composite sleep health scores in 413,904 individuals.
Authors: Goodman MO, Faquih T, Paz V, Nagarajan P, Lane JM, Spitzer B, Maher M, Chung J, Cade BE, Purcell SM, Zhu X, Noordam R, Phillips AJK, Kyle SD, Spiegelhalder K, Weedon MN, Lawlor DA, Rotter JI, Taylor KD, Isasi CR, Sofer T, Dashti HS, Rutter MK, Redline S, Saxena R, Wang H.
Commun Biol
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Commun Biol
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Polygenic Risk Scores: Coming to Your Operating Room?
Siesta behavior and genetics interact to influence obesity risk.
Authors: Rodríguez-Martín M, Salmerón D, Dashti HS, Isabel Cascales A, Aragón-Alonso A, Scheer FAJL, Saxena R, Garaulet M.
Obesity (Silver Spring)
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Obesity (Silver Spring)
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Clinical and genetic associations for night eating syndrome in a patient biobank.
A conserved role for ALG10/ALG10B and the N -glycosylation pathway in the sleep-epilepsy axis.
Authors: Gill S, Mandigo TR, Elmali AD, Leger BS, Yang B, Tran S, Laosuntisuk K, Lane JM, Bannister D, Aonbangkhen C, Ormerod KG, Mahama B, Schuch KN, Elya C, Akhund-Zade J, Math SR, LoRocco NC, Seo S, Maher M, Kanca O, Bebek N, Karadeniz D, Senel GB, Courage C, Lehesjoki AE, Winkelman JW, Bellen HJ, de Bivort B, Hart AC, Littleton JT, Baykan B, Doherty CJ, Melkani GC, Prober DA, Woo CM, Saxena R, Schreiber SL, Walker JA.
medRxiv
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medRxiv
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An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype.
Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype.
Authors: Nagarajan P, Kurniansyah N, Lee J, Gharib SA, Xu Y, Zhang Y, Spitzer B, Faquih T, Zhou H, Boerwinkle E, Chen H, Gottlieb DJ, Guo X, Heard-Costa NL, Hidalgo BA, Levy D, Liu PY, Mei H, Montalvan R, Mukherjee S, North KE, O'Conner GT, Palmer LJ, Patel SR, Psaty BM, Purcell SM, Raffield LM, Rich SS, Rotter JI, Saxena R, Smith AV, Stone KL, Zhu X, Cade BE, Sofer T, Redline S, Wang H.
medRxiv
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medRxiv
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Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals.
Authors: Windred DP, Burns AC, Lane JM, Olivier P, Rutter MK, Saxena R, Phillips AJK, Cain SW.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Sleep inertia drives the association of evening chronotype with psychiatric disorders: epidemiological and genetic evidence.
Authors: Burns AC, Zellers S, Windred DP, Daghlas I, Sinnott-Armstrong N, Rutter M, Hublin C, Friligkou E, Polimanti R, Phillips AJK, Cain SW, Kaprio J, Ollila HM, Saxena R, Lane JM.
medRxiv
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medRxiv
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Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.
Authors: Tervi A, Ramste M, Abner E, Cheng P, Lane JM, Maher M, Valliere J, Lammi V, Strausz S, Riikonen J, Nguyen T, Martyn GE, Sheth MU, Xia F, Docampo ML, Gu W, Esko T, Saxena R, Pirinen M, Palotie A, Ripatti S, Sinnott-Armstrong N, Daly M, Engreitz JM, Rabinovitch M, Heckman CA, Quertermous T, Jones SE, Ollila HM.
Cell Genom
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Cell Genom
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