Harvard Title
Professor of Anaesthesia
Administrative and Hospital Titles
Associate Geneticist, Center for Genomic Medicine Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital
Director of Genetics of Sleep and Circadian Research Program in Sleep Epidemiology, Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital
Associate Member, Broad Institute
Address
Massachusetts General Hospital
Simches Research Ctr
185 Cambridge Street, CPZN 5.802
Boston, MA 02114
Publications View
Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype.
Authors: Nagarajan P, Kurniansyah N, Lee J, Gharib SA, Xu Y, Zhang Y, Spitzer B, Faquih T, Zhou H, Boerwinkle E, Chen H, Gottlieb DJ, Guo X, Heard-Costa NL, Hidalgo BA, Levy D, Liu PY, Mei H, Montalvan R, Mukherjee S, North KE, O'Conner GT, Palmer LJ, Patel SR, Psaty BM, Purcell SM, Raffield LM, Rich SS, Rotter JI, Saxena R, Smith AV, Stone KL, Zhu X, Cade BE, Sofer T, Redline S, Wang H.
medRxiv
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medRxiv
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Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals.
Authors: Windred DP, Burns AC, Lane JM, Olivier P, Rutter MK, Saxena R, Phillips AJK, Cain SW.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Sleep inertia drives the association of evening chronotype with psychiatric disorders: epidemiological and genetic evidence.
Authors: Burns AC, Zellers S, Windred DP, Daghlas I, Sinnott-Armstrong N, Rutter M, Hublin C, Friligkou E, Polimanti R, Phillips AJK, Cain SW, Kaprio J, Ollila HM, Saxena R, Lane JM.
medRxiv
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medRxiv
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Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.
Authors: Tervi A, Ramste M, Abner E, Cheng P, Lane JM, Maher M, Valliere J, Lammi V, Strausz S, Riikonen J, Nguyen T, Martyn GE, Sheth MU, Xia F, Docampo ML, Gu W, Esko T, Saxena R, Pirinen M, Palotie A, Ripatti S, Sinnott-Armstrong N, Daly M, Engreitz JM, Rabinovitch M, Heckman CA, Quertermous T, Jones SE, Ollila HM.
Cell Genom
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Cell Genom
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Placental Origins of Preeclampsia: Insights from Multi-Omic Studies.
Melatonin decreases human adipose tissue insulin sensitivity.
Authors: Zambrano C, Garitaonaindia MT, Salmerón D, Pérez-Sanz F, Tchio C, Picinato MC, de Medina FS, Luján J, Scheer FAJL, Saxena R, Martínez-Augustin O, Garaulet M.
J Pineal Res
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J Pineal Res
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Genetic variants affect diurnal glucose levels throughout the day.
Authors: Sinnott-Armstrong N, Strausz S, Urpa L, Abner E, Valliere J, Palta P, Dashti HS, Daly M, Pritchard JK, Saxena R, Jones SE, Ollila HM.
bioRxiv
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bioRxiv
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Personal light exposure patterns and incidence of type 2 diabetes: analysis of 13 million hours of light sensor data and 670,000 person-years of prospective observation.
Authors: Windred DP, Burns AC, Rutter MK, Ching Yeung CH, Lane JM, Xiao Q, Saxena R, Cain SW, Phillips AJK.
Lancet Reg Health Eur
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Lancet Reg Health Eur
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The role of accelerometer-derived sleep traits on glycated haemoglobin and glucose levels: a Mendelian randomization study.
Authors: Liu J, Richmond RC, Anderson EL, Bowden J, Barry CS, Dashti HS, Daghlas IS, Lane JM, Kyle SD, Vetter C, Morrison CL, Jones SE, Wood AR, Frayling TM, Wright AK, Carr MJ, Anderson SG, Emsley RA, Ray DW, Weedon MN, Saxena R, Rutter MK, Lawlor DA.
Sci Rep
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Sci Rep
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Impact of insomnia on ovarian cancer risk and survival: a Mendelian randomization study.
Authors: Wang H, Reid BM, Richmond RC, Lane JM, Saxena R, Gonzalez BD, Fridley BL, Redline S, Tworoger SS, Wang X, Wang H, Reid BM, Richmond RC, Lane JM, Saxena R, Gonzalez BD, Fridley BL, Redline S, Tworoger SS, Wang X, Wang H, Reid BM, Richmond RC, Lane JM, Saxena R, Gonzalez BD, Fridley BL, Redline S, Tworoger SS, Wang X.
EBioMedicine
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EBioMedicine
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