Harvard Title

Professor of Anaesthesia

Administrative and Hospital Titles

Associate Geneticist, Center for Genomic Medicine Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital
Director of Genetics of Sleep and Circadian Research Program in Sleep Epidemiology, Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital
Associate Member, Broad Institute

Address

Massachusetts General Hospital
Simches Research Ctr
185 Cambridge Street, CPZN 5.802
Boston, MA 02114

Publications View
Genome-wide association analysis of composite sleep health scores in 413,904 individuals.
Authors: Goodman MO, Faquih T, Paz V, Nagarajan P, Lane JM, Spitzer B, Maher M, Chung J, Cade BE, Purcell SM, Zhu X, Noordam R, Phillips AJK, Kyle SD, Spiegelhalder K, Weedon MN, Lawlor DA, Rotter JI, Taylor KD, Isasi CR, Sofer T, Dashti HS, Rutter MK, Redline S, Saxena R, Wang H.
Commun Biol
View full abstract on Pubmed
Polygenic Risk Scores: Coming to Your Operating Room?
Authors: Kovacheva VP, Saxena R.
Anesthesiology
View full abstract on Pubmed
Siesta behavior and genetics interact to influence obesity risk.
Authors: Rodríguez-Martín M, Salmerón D, Dashti HS, Isabel Cascales A, Aragón-Alonso A, Scheer FAJL, Saxena R, Garaulet M.
Obesity (Silver Spring)
View full abstract on Pubmed
Clinical and genetic associations for night eating syndrome in a patient biobank.
Authors: Wilcox H, Saxena R, Winkelman JW, Dashti HS.
J Eat Disord
View full abstract on Pubmed
A conserved role for ALG10/ALG10B and the N -glycosylation pathway in the sleep-epilepsy axis.
Authors: Gill S, Mandigo TR, Elmali AD, Leger BS, Yang B, Tran S, Laosuntisuk K, Lane JM, Bannister D, Aonbangkhen C, Ormerod KG, Mahama B, Schuch KN, Elya C, Akhund-Zade J, Math SR, LoRocco NC, Seo S, Maher M, Kanca O, Bebek N, Karadeniz D, Senel GB, Courage C, Lehesjoki AE, Winkelman JW, Bellen HJ, de Bivort B, Hart AC, Littleton JT, Baykan B, Doherty CJ, Melkani GC, Prober DA, Woo CM, Saxena R, Schreiber SL, Walker JA.
medRxiv
View full abstract on Pubmed
An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype.
Authors: Tchio C, Williams J, Taylor H, Ollila H, Saxena R.
bioRxiv
View full abstract on Pubmed
Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype.
Authors: Nagarajan P, Kurniansyah N, Lee J, Gharib SA, Xu Y, Zhang Y, Spitzer B, Faquih T, Zhou H, Boerwinkle E, Chen H, Gottlieb DJ, Guo X, Heard-Costa NL, Hidalgo BA, Levy D, Liu PY, Mei H, Montalvan R, Mukherjee S, North KE, O'Conner GT, Palmer LJ, Patel SR, Psaty BM, Purcell SM, Raffield LM, Rich SS, Rotter JI, Saxena R, Smith AV, Stone KL, Zhu X, Cade BE, Sofer T, Redline S, Wang H.
medRxiv
View full abstract on Pubmed
Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals.
Authors: Windred DP, Burns AC, Lane JM, Olivier P, Rutter MK, Saxena R, Phillips AJK, Cain SW.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Sleep inertia drives the association of evening chronotype with psychiatric disorders: epidemiological and genetic evidence.
Authors: Burns AC, Zellers S, Windred DP, Daghlas I, Sinnott-Armstrong N, Rutter M, Hublin C, Friligkou E, Polimanti R, Phillips AJK, Cain SW, Kaprio J, Ollila HM, Saxena R, Lane JM.
medRxiv
View full abstract on Pubmed
Genetic and functional analysis of Raynaud's syndrome implicates loci in vasculature and immunity.
Authors: Tervi A, Ramste M, Abner E, Cheng P, Lane JM, Maher M, Valliere J, Lammi V, Strausz S, Riikonen J, Nguyen T, Martyn GE, Sheth MU, Xia F, Docampo ML, Gu W, Esko T, Saxena R, Pirinen M, Palotie A, Ripatti S, Sinnott-Armstrong N, Daly M, Engreitz JM, Rabinovitch M, Heckman CA, Quertermous T, Jones SE, Ollila HM.
Cell Genom
View full abstract on Pubmed