Harvard Title
Associate Professor of Psychiatry
Other Affiliations
Department of Psychiatry, Brigham and Women's Hospital
Senior Associate, Broad Institute, Stanley Center for Psychiatric Research
Address
Brigham and Women's Hospital
Dept. of Psychiatry, Rm 394
221 Longwood Ave
Boston MA 02115
Publications View
Antidepressant response and polygenes.
Implication of a rare deletion at distal 16p11.2 in schizophrenia.
Authors: Guha S, Rees E, Darvasi A, Ivanov D, Ikeda M, Bergen SE, Magnusson PK, Cormican P, Morris D, Gill M, Cichon S, Rosenfeld JA, Lee A, Gregersen PK, Kane JM, Malhotra AK, Rietschel M, Nöthen MM, Degenhardt F, Priebe L, Breuer R, Strohmaier J, Ruderfer DM, Moran JL, Chambert KD, Sanders AR, Shi J, Kendler K, Riley B, O'Neill T, Walsh D, Malhotra D, Corvin A, Purcell S, Sklar P, Iwata N, Hultman CM, Sullivan PF, Sebat J, McCarthy S, Gejman PV, Levinson DF, Owen MJ, O'Donovan MC, Lencz T, Kirov G.
JAMA Psychiatry
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JAMA Psychiatry
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Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.
Authors: Lim ET, Raychaudhuri S, Sanders SJ, Stevens C, Sabo A, MacArthur DG, Neale BM, Kirby A, Ruderfer DM, Fromer M, Lek M, Liu L, Flannick J, Ripke S, Nagaswamy U, Muzny D, Reid JG, Hawes A, Newsham I, Wu Y, Lewis L, Dinh H, Gross S, Wang LS, Lin CF, Valladares O, Gabriel SB, dePristo M, Altshuler DM, Purcell SM, State MW, Boerwinkle E, Buxbaum JD, Cook EH, Gibbs RA, Schellenberg GD, Sutcliffe JS, Devlin B, Roeder K, Daly MJ.
Neuron
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Neuron
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Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia.
Authors: Kim Y, Ripke S, Kirov G, Sklar P, Purcell SM, Owen MJ, O'Donovan MC, Sullivan PF.
Schizophr Res
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Schizophr Res
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Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities.
Authors: Talkowski ME, Maussion G, Crapper L, Rosenfeld JA, Blumenthal I, Hanscom C, Chiang C, Lindgren A, Pereira S, Ruderfer D, Diallo AB, Lopez JP, Turecki G, Chen ES, Gigek C, Harris DJ, Lip V, An Y, Biagioli M, Macdonald ME, Lin M, Haggarty SJ, Sklar P, Purcell S, Kellis M, Schwartz S, Shaffer LG, Natowicz MR, Shen Y, Morton CC, Gusella JF, Ernst C.
Am J Hum Genet
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Am J Hum Genet
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Highly penetrant alterations of a critical region including BDNF in human psychopathology and obesity.
Authors: Ernst C, Marshall CR, Shen Y, Metcalfe K, Rosenfeld J, Hodge JC, Torres A, Blumenthal I, Chiang C, Pillalamarri V, Crapper L, Diallo AB, Ruderfer D, Pereira S, Sklar P, Purcell S, Wildin RS, Spencer AC, Quade BF, Harris DJ, Lemyre E, Wu BL, Stavropoulos DJ, Geraghty MT, Shaffer LG, Morton CC, Scherer SW, Gusella JF, Talkowski ME.
Arch Gen Psychiatry
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Arch Gen Psychiatry
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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder.
Authors: Lee PH, Perlis RH, Jung JY, Byrne EM, Rueckert E, Siburian R, Haddad S, Mayerfeld CE, Heath AC, Pergadia ML, Madden PA, Boomsma DI, Penninx BW, Sklar P, Martin NG, Wray NR, Purcell SM, Smoller JW.
Transl Psychiatry
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Transl Psychiatry
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Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth.
Authors: Fromer M, Moran JL, Chambert K, Banks E, Bergen SE, Ruderfer DM, Handsaker RE, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G, Sullivan PF, Hultman CM, Sklar P, Purcell SM.
Am J Hum Genet
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Am J Hum Genet
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Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Authors: Lips ES, Cornelisse LN, Toonen RF, Min JL, Hultman CM, Holmans PA, O'Donovan MC, Purcell SM, Smit AB, Verhage M, Sullivan PF, Visscher PM, Posthuma D.
Mol Psychiatry
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Mol Psychiatry
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zCall: a rare variant caller for array-based genotyping: genetics and population analysis.
Authors: Goldstein JI, Crenshaw A, Carey J, Grant GB, Maguire J, Fromer M, O'Dushlaine C, Moran JL, Chambert K, Stevens C, Sklar P, Hultman CM, Purcell S, McCarroll SA, Sullivan PF, Daly MJ, Neale BM.
Bioinformatics
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Bioinformatics
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