2020 Sleep and Health Benefit
On December 7, 2020, the Division of Sleep Medicine held its 19th Annual Sleep and Health Benefit virtually, given the COVID-19 pandemic and recommended social distancing guidelines within our Harvard Medical School community. Mary A. Carskadon, PhD, Professor of Psychiatry and Human Behavior at Warren Alpert Medical School of Brown University, and Director of the Sleep and Chronobiology Research Lab at Bradley Hospital was awarded the2020 Harvard Medical School Division of Sleep Medicine Prize for her contributions to the field of Sleep Medicine. Charles A. Czeisler, MD, PhD, Baldino Professor of Sleep Medicine, Director of the Division of Sleep Medicine at Harvard Medical School and Chief of the Division of Sleep and Circadian Disorders in the Department of Medicine at Brigham and Women's Hospital in Boston, Massachusetts, presented opening remarks. Clif Saper, MD, PhD, James Jackson Putnam Professor of Neurology and Neuroscience at Harvard Medical School and Chair and Head of the Department of Neurology at Beth Israel Deaconess Medical Center, presented the award.
Support for the 2020 Sleep and Health Benefit Dinner was generously provided by the following individuals and organizations:
| Benefactors |
Sleep Number |
Harmony Biosciences |
| Leader | Sleep Cycle | |
| Sponsors |
Timeshifter |
Kun Hu, Ph.D. |
| Supporters |
Takeda Pharmaceuticals |
Dara S. Manoach, Ph.D. |
Support in 2020 for the Harvard Medical School Division of Sleep Medicine Sleep Grand Rounds Program was generously provided by the following individuals and organizations:
- Harmony Biosciences, LLC
- Jazz Pharmaceuticals
- Regional Home Care
- NeuroCare, Inc.
- Philips Respironics
- Arbor Pharmaceuticals
For over 23 years, support for the Harvard Medical School Training Program in Sleep, Circadian and Respiratory Neurobiology administered by the Brigham and Women’s Hospital has been provided by a training grant from the National Heart, Lung and Blood Institute.
The previous schedule for the day-of events can be found below:
SCHEDULE
10:00 - 11:30 AM ET
HMS DSM Annual Faculty Meeting
10:00 - 11:30 AM ET
Mary A. Carskadon, PhD Introductory Meeting with HMS DSM Trainees
12:00 - 1:15 PM ET
Division of Sleep Medicine Annual Prize Lecture by Mary A. Carskadon, PhD
“Sleepiness, Sleep, Circadian Timing, and Adolescent Sleep: A Career Perspective”
Mary A. Carskadon, PhD
Professor of Psychiatry and Human Behavior
Department of Psychiatry and Human Behavior,
Warren Alpert Medical School of Brown University
Director of the Sleep and Chronobiology Research Lab
Bradley Hospital
- Opening Remarks: Charles A. Czeisler, MD, PhD
Access the recording of the lecture by clicking here.
1:15 - 1:30 PM ET
Awarding of 2020 Harvard Medical School Division of Sleep Medicine Prize to Mary A. Carskadon, PhD
- Award Presentation: Clif Saper, MD, PhD
3:00 - 4:30 PM ET
4:30 - 5:30 PM ET
Reception
- Opening Remarks: Charles A. Czeisler, MD, PhD
- Poster Award Presentations: Thomas E. Scammell, MD
6:00 - 7:00 PM ET
Evening Public Lecture by Mary A. Carskadon, PhD
“Changes in Sleep Biology Create a Perfect Storm Affecting Teen Health and Well-Being”
- Opening Remarks: Charles A. Czeisler, MD, PhD
- Moderator: Judith A. Owens, MD, MPH
Register now ! Have questions related to the lecture? Submit your questions here!
Access the recording of the public lecture by clicking here.
Poster Session
Basic Science and Biomarkers
| Winner | Honorable Mention |
| Michael Gulledge | Leilah Grant, Ph.D. |
- Lindsey Brown, S.M. - A Classification Approach to DLMO Prediction
- Leilah Grant, Ph.D. - Circadian and Diurnal Triglyceride Rhythms are Antiphasic: Implications for Meal Timing & Dyslipidemia in Shift Workers
- Michael Gulledge, graduate student - Determining the behavioral and Neurobiological Effects of Oxycodone Withdrawal on Sleep
- Judith Kaye, B.S. - Molecular Diversity of Peripheral Sensory Neurons and their Role in Breathing
- Brianne Kent, Ph.D. - Peripheral Circadian Rhythms Shift with a Phase Response Curve Different than Melatonin
- Mudasir Khanday, Ph.D. - Role of Parabrachial Neurons in Regulation of Arousal
- Natalia Machado, Ph.D. - Median Preoptic GABA and Glutamate Neurons Exert Differential Control over Sleep Behavior
- Carrie Mahoney, Ph.D. - Cataplexy Triggered by Social Cues: A Role of Oxytocin in the Amygdala
- Marlen Menlyadiev, Ph.D. - Real-Time Breath Metabolomics for Circadian Time Determination
- Emmanuel Mignot, M.D., Ph.D. - Proteomics of Sleep and Circadian Biology
- Nikita Sturrock, B.S. - Dorsal Raphe Heterogeneity: Characterization of a Purine Receptor Expressing Subpopulation of Serotonin Neurons
- Huan Yang, Ph.D. - Increased Sodium Excretion and Urinary Output during Acute Human Sleep Deprivation
Breathing, Cardiovascular, and Clinical Sleep Disorders
| Winner | Honorable Mention |
| Shuqiang Chen, M.A. | Mark Czeisler, A.B. |
- Margaret Blattner, M.D., Ph.D. - Quantification of Late REM Periods in Patients with Prolonged Sleep Duration
- Brian Cade, Ph.D. - Sleep Apnea and COVID-19 Mortality and Hospitalization
- Alice Cai, M.D. - Use of PAP Data as a Sleep Diary
- Shuqiang Chen, M.A. - Quantitative Characterization of Sleep Disordered Breathing Dynamics
- Joon Chung, Ph.D. - Multidimensional Sleep Heath, Incident CVD and Mortality: Multi-Ethnic Study of Atherosclerosis
- Mark Czeisler, A.B. - Disruptions to Sleep and Behaviors Alongside Adverse Mental Health Symptoms: Acute Changes During the COVID-19 Pandemic in the United States and Australia
- Larissa Engert, Ph.D. - Exposure to Experimentally Induced Sleep Disturbance Affects the Inflammatory Resolution Pathways in Healthy Humans
- Matthew Goodman, M.S., Ph.D - Pathway-Specific Polygenic Risk Scores (PGRS) Identify CVD Pathways Moderated by OSA
- Heidi Lammers van der Holst, Ph.D. - Sex Differences in Sleep and Quality of Life in Healthcare Shift Workers
- Rebecca Robbins, Ph.D. - Smartphone Application-Estimated Sleep Duration during COVID-19 in Five Major Metropolitan Areas Across 3 Million Nights on Three Different Continents
- Michael Vasquez, undergraduate - Sleep Hygiene as an Intervention to Lower Blood Pressure
- Daniel Vena, Ph.D. - Associations of Clinical Polysomnographic Methods of Quantifying Collapsibility in Obstructive Sleep Apnea Airflow Shape and Snore Sounds on Site of Pharyngeal Collapse
- Benjamin Wipper, B.A. - The National RLS Opioid Registry: An Observational Study Examining the Safety and Efficacy of Long-Term Opioid Treatment of Restless Leg Syndrome
- Hui-Wen Yang, Ph.D - Reduced Daily Rhythm of Fractal Cardiac Dynamics Is Associated with Weight Loss Resistance in Overweight/Obese Patients
Memory, Cognition, and EEG
| Winner | Honorable Mention |
| Bryan Baxter, Ph.D. | Megan Thompson, Ph.D. |
- Bryan Baxter, Ph.D. - Evaluating Closed-Loop Auditory Stimulation during Sleep as an Intervention to Improve Memory Consolidation
- Ryan Bottary, M.A., Ph.D. Candidate - Behavioral and Neural Correlates of Emotional Memory Retrieval Following a Daytime Nap
- Tony Cunningham, Ph.D. - The Effects of Sleep Apnea on Emotional Memory Consolidation
- Michael Goldstein, Ph.D. - Sleep Spindles Harmonics in Insomnia
- Hyeonjin Kim - Quantitative Phenotype of Brain Activity During Sleep Represented by EEG Power Spectral Density as a Function of Slow Oscillation Dynamics
- Emmanuelle Pardilla-Delgado, Ph.D. - Decreased Actigraphic Daytime Activity is Associated with Lower Memory Performance in Cognitively-Unimpaired Individuals with Autosomal Dominant Alzheimer's Disease
- Rebecca Robbins, Ph.D. - Examining Sleep Deficiency and Disturbance and their Risk for Incidental Dementia and All-cause Mortality in Older Adults Across 5 years in the United States
- Haoqi Sun, Ph.D. - Potential Sleep EEG-Based Biomarkers for Brain Health & Randomness in Motor Fluctuations at Time Scales Shorter than 10 Minutes Predict Alzheimer's Dementia
- Megan Thompson, Ph.D. - Coordination of Neural Oscillations in Patients with Hippocampal Intracranial Electrodes in Relation to Sleep-Dependent Memory Consolidation
- Thomas Xin - Impact of Chronic Sleep Restriction on Sleep Continuity, Sleep Structure, and Neurobehavioral Performance